呼吸道感染病原菌分布及耐药性分析

呼吸道感染病原菌分布及耐药性分析(论文4200字)
摘 要
目的：了解呼吸道感染患者的病原菌分布及其耐药性 ,指导临床合理用药。方法  2016 年 7 月-2017 年 5 月住院呼吸道感染患者痰培养结果 。结果400株病原菌 G- 菌占70%、G+ 菌占 16%、真菌占 14%。铜绿假单胞菌 、鲍曼不动杆菌、大肠埃希氏菌、金黄色葡萄球菌和肺炎克雷伯氏菌为主要细菌 ,革兰氏阳性球菌对万古霉素、米诺环素和利福平较为敏感, 而革兰氏阴性杆菌对美洛培南、亚胺培南和阿米卡星的敏感性较高。常见 G+、G- 菌的耐药性有上升趋势 ,且具有多重耐药性。结论 在治疗感染性疾病时应进行病原学检查,依据药敏试验结果合理使用抗生素 ,以减少耐
关键词：痰培养;　 呼吸道感染;　 药物敏感试验
 
ABSTRACT
Objective:  To investigate the pathogenic change in respiratory tract infection (RTI)in inpatientsand to provide reference for clinical treatment . Methods　 analysiswas conducted on sputum culti-vation results of RTI patientswho were hospitalized from July 2016 to May 2017.　 Results  400 strainswereisolated from.Gram -positive microorganisms accounted for 16%(64),Gram -negative microorganisms accounted for 70%(280),and fungi accounted for14%(56).The main pathogens were Pseudomonas aeruginosa ,Acinetobacter baumannii , Escherichia coli ,Staphy-lococcus aureus and klebsiella pneumoniae .The sensitive drugs of Gram -positive microorganisms were vancomycin,rifampicin,and minocyline .While the sensitive drugs of Gram -negative microorganisms were Meropenem imipen-em ,and amikacin .The drug resistance rate was increasing and some bacteria were multi drug resistance strains.Conclusion 　In order to reduce drug resistance strains,it is important that bacterial culture should be carried outactively and antibiotics administration must be based on the drug sensitivity test of clinical significance.
Key words:　 sputum cultivation;　 RTI;　 drug sensitivity test

目录
中文摘要    Ⅰ
英文摘要    Ⅱ
前言    1
正文    3
1 材料与方法    3
1.1 研究对象    3
1. 2 研究方法    3
1.2.1 采集临床样本    3
1.2.2 分离鉴定与药敏试验    3
1.2.3 病原菌的分离结果    3
1.3 药敏情况……………………………………………………………………3
2 结果    4
2.1病原菌的分离结果…………………………………………….. 4
2.2药敏情况…………………………………………………….. ...4
3 讨论    6
结论    8
参考文献    9
致谢    11
综述    12