裙带菜可溶性膳食纤维对小鼠脂质异常的影响

裙带菜可溶性膳食纤维对小鼠脂质异常的影响(5000字)
摘  要：目的： 研究裙带菜可溶性膳食纤维对载脂蛋白E缺陷小鼠脂质异常的影响。方法： 40只小鼠分为4组(n=10): 对照组(C57BL/6J小鼠)；高脂模型组(载脂蛋白E缺陷小鼠)，膳食纤维低剂量组(5%)，膳食纤维高剂量组(10%)；经裙带菜可溶性膳食纤维处理8周后，检测血浆和肝脏脂类水平。结果： 裙带菜可溶性膳食纤维显著降低血浆和肝脏TG、TC、增加血浆HDL-C水平。结论：裙带菜可溶性膳食纤维能改善载脂蛋白E缺陷小鼠脂质异常。
关键词：裙带菜；可溶性膳食纤维；载脂蛋白E缺陷小鼠

THE EFFECT OF UNDARIA PINNATIFIDA DIETARY FIBER ON DYSLIPIDEMIA IN MICE

Abstract: Objective:To test the effect of Undaria pinnatifida soluble dietary fiber on dyslipidemia in apolipoprotein E deficient mice. Method:40 mice were divided into 4 groups (n=10): control group (C57BL/6J mice), high lipids group(apolipoprotein E deficient mice), low dose dietary fiber-treated group (5%), high dose dietary fiber -treated group(10%). After treatment of undaria pinnatifida soluble dietary fiber for 8 weeks, the contents of plasma and hepatic lipids was determined.  Results:Undaria pinnatifida soluble dietary fiber treatment significantly decreased the levels of plasma and hepatic TC, TG, but significantly increased the plasma HDL-C level. Conclusion: Undaria pinnatifida soluble dietary fiber has the beneficial effect on dyslipidemia of apolipoprotein E deficient mice.
Key words: Undaria pinnatifida; Soluble dietary fiber; apolipoprotein E deficient mice

目  录
摘  要    1
关键词    1
1  前言    2
2  材料与方法    2
2.1  待检样本及试剂    2
2.2  实验动物及分组    3
2.3  血脂水平检测    3
2.4  肝脂质浓度检测    3
2.5  统计分析    3
3  结  果    3
3.1  血脂水平    3
3.2  肝脂浓度    3
4  讨  论    4
参 考 文 献    6
致    谢    7